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Biomedical Sciences (BMS)

Course Descriptions

Predoctoral Courses

AN 110. Human Anatomy I: Cells to Systems. 6 Units.

The student will gain an understanding of cell biology, functional histology, and gross anatomy of the human body as appropriate for professional health care providers. Emphasis will be on the integration of anatomical knowledge at all levels and its correlation with basic clinical medicine relevant to dentistry. (45 hours lecture, 40 hours laboratory, including 15 hours clinical correlations/case discussion. Quarters 1-2.).

AN 111. Human Anatomy II: The Orofacial Complex. 7 Units.

The student will gain an understanding of the embryology, histology, neuroanatomy and gross anatomy of the head and neck as appropriate for a dental professional. The objectives are for the student to (1) understand the normal development and structure of tissues of the head and neck in preparation for courses in oral pathology and oral medicine and (2) comprehend the biological basis for rational diagnosis and treatment of clinical problems. Emphasis will be on the integration of anatomical knowledge and its correlation with oral medicine and clinical dentistry (40 hours lecture, 40 hours laboratory, 20 hours seminar/case discussion, Quarter 3).

BC 114. Biochemistry. 6 Units.

Study of major molecular structures and processes of the human organism including structure, function, and biosynthesis of the informational macromolecules, proteins and nucleic acids; generation and storage of metabolic energy; structure, genesis, and transformations of mineralized tissues; and digestion, absorption, and utilization of required nutrients. (60 hours lecture, including 10 hours case-based discussion. Quarters 1-2.).

BMS 121. Clinical Pharmacology and Pathology. 3 Units.

This course focuses on the action of therapeutic drugs on dental patients. In addition, the most commonly found pathologic lesions (red and white, ulcerative, etc) will be discussed. This three-quarter course covers the general principles of drug action, including drug absorption, distribution, metabolism, elimination, and pharmacodynamics of important therapeutic drug categories in combination with the most commonly found oral lesions. The dental implications of therapeutic drugs and commonly found oral lesions will be emphasized and discussed using a seminar, case-based format. (IDS Quarters 1, 2 and 3).

BMS 122. A Multidisciplinary Approach to Clinical Diagnosis and Treatment Planning. 1 Unit.

This course is meant to integrate and apply various disciplines to the diagnosis and treatment planning process. In this interactive class, students will be presented cases with medical-dental, anatomic, pain problems, and psychological issues to discuss. Students in small groups will workup cases and present their diagnostic conclusions and treatment plans to the larger group. The faculty will facilitate and provide feedback on the student conclusions and plans. Students will learn: Commonly encountered medical problems, system disorders, and potential drug interactions in practice and the modifications to be considered in treatment decisions. The anatomy of the oromaxillofacial complex and its relationship to diagnosis and treatment. Diagnosis of orofacial lesions and TMD dysfunction and their effect on treatment The role of the specialist in the diagnostic process and when to consult or refer patients to specialists in patient care. (IDS Quarter 4).

MC 224. Microbiology. 9 Units.

The biology of microorganisms that cause disease, including caries, and periodontal and endodontic infections. Microbial structure, metabolism, genetics, and virulence factors; molecular diagnostics and recombinant DNA technology. Pathogenesis, epidemiology, clinical syndromes, laboratory diagnosis, treatment, and prevention of infectious diseases. Innate, humoral and cell-mediated immunity, hypersensitivity and vaccines. Antibacterial, antiviral and antifungal agents. Bacterial infections, including oral manifestations; oral microbiology. Virology, with emphasis on HIV, herpes viruses, and hepatitis viruses; oral manifestations of viral infections. Mycology, with emphasis on oral infections. Parasitology, with emphasis on global public health. Microbiology laboratory, focusing on the human skin and oral microbiome. (57 lecture hours, including discussions and independent study hours. Quarters 4-5.).

PG 120. Physiology. 7 Units.

Study of the functioning of the human body, basic methods used to evaluate physiological parameters and introduction to recognition of functional abnormalities in humans. Cell membrane transport; electrical potentials; peripheral nerves; skeletal and smooth muscles; spinal cord and autonomic nervous system; circulatory system and respiratory system; homeostatic function of the kidneys; energy metabolism, temperature regulation, assimilation of food by the gastrointestinal tract; regulatory function of the endocrine system; perception of the external world through the sense organs, and integrative activity of the brain. (70 hours lecture and demonstrations including 10 hours case-based discussion. Quarters 1-3.).

PG 220. Pharmacology and Therapeutics. 6 Units.

Rationale of drug use in dental practice, and mechanisms of action of drugs used for the medical management of dental patients; pharmacodynamics and drug kinetics; quantitative pharmacology; drug laws and regulations; prescription writing; emergency drugs, autonomic, respiratory, cardiovascular, psychotropic, hormonal, gastrointestinal, antianxiety, antiparkinson, antidiabetic, antineoplastic drugs; neuromuscular blockers, histamine antagonists, inflammatory mediators, sedative- hypnotics, anticonvulsants, general and local anesthetics, analgesics, antibiotics, antifungal and antiviral agents, substance abuse, toxicology, drug interactions, and therapeutic decision making. (60 hours lecture. Quarters 6-8.).

Graduate Courses

AN 410. Advanced Head and Neck Anatomy I. 1 Unit.

This course presents head and neck anatomy in depth to provide residents essential foundation for dental procedures. The development of normal and pathological craniofacial shapes, as well as anatomical structures relevant for implant placement, are discussed in detail. (Quarter 1.).

BC 414. Biochemistry and Bioengineering I. 1 Unit.

Residents learn how to assess biocompatibility and longevity of various materials in contact with body fluid and tissues. This course also covers biofilm formation and removal from oral biomaterials. (Quarter 2.).

BMS 401. Research Philosophy and Design I. 1 Unit.

In this two-quarter foundational course, students learn about hypothesis-driven research, including hypothesis development and significance testing. (Quarter 1.).

BMS 411. Stem Cell Biology I. 1 Unit.

In this two-quarter course, residents discuss in detail current research on cell populations, their properties, and possible application routes--the foundation of modern biology-driven endodontic therapy. Treatment possibilities for immature teeth and other applications in regenerative endodontics are presented. (Quarter 2.).

BMS 412. Topics in Oral Biology I. 1 Unit.

This course covers the interaction of pulpal and periapical tissues with medicaments such as bisphosphonates or TNF-alpha blocking antibodies, the effects of systemic diseases such as HIV, diabetes or sclerodermia on oral tissues, and other common issues in endodontics. (Quarter 4.).

BMS 414. Oral Biology Journal Club I. 3 Units.

This course features discussion of papers on a variety of topics in oral biology.(Quarters 2-4.).

BMS 440. Thesis Protocol. 1 Unit.

In this independent-study research course, residents work with mentor(s) to develop research questions, formulate hypotheses, and write a formal research proposal that includes a full literature review, statement of material and methods, execution of the research, and appropriate analysis and interpretation of data. (Quarter 2.).

BMS 450. Research Project I. 3 Units.

In this independent-study research course, residents work with research mentors to perform the research project, including data gathering, complilation, and interpretation of the results. The course will culminate in a publishable manuscript.(Quarters 1-4.).

BMS 512. Topics in Oral Biology II. 1 Unit.

This course covers the interaction of pulpal and periapical tissues with medicaments such as bisphosphonates or TNF-alpha blocking antibodies, the effects of systemic diseases such as HIV, diabetes or sclerodermia on oral tissues, and other common issues in endodontics. (Quarter 8.).

BMS 514. Oral Biology Journal Club II. 3 Units.

Residents read and discuss current literature on a range of oral biology topics. (Quarters 6-8.).

BMS 550. Research Project II. 3 Units.

In this independent-study research course, residents work with research mentors to perform the research project, including data gathering, complilation, and interpretation of the results. The course will culminate in a publishable manuscript. (Quarters 5-8.).

BMS 651. Manuscript Preparation. 3 Units.

Residents prepare the final version of a publishable manuscript. (Quarter 9.).

MC 404. Host Response I. 1 Unit.

This course extends basic immunology to the etiology of pulpal and periapical disease focusing on the host response. The role of inflammatory mediators and the cells that elaborate them is discussed. (Quarter 1.).

MC 424. Oral Microbiology I. 1 Unit.

Residents learn about microbial structure, metabolism, genetics, and virulence factors; molecular diagnostics and recombinant DNA technology; pathogenesis, epidemiology, clinical syndromes, laboratory diagnosis, treatment, and prevention of infectious diseases. (Quarter 2.).

MC 504. Host Response II. 1 Unit.

This course extends from basic immunology to the etiology of pulpal and periapical disease focusing on the host response. The role of inflammatory mediators and the cells that elaborate them will be discussed. (Quarter 5.).

PG 420. Advanced Pharmacology I. 1 Unit.

Local anesthesia and pain management of acute and chronic pain are main components of this lecture series, with specific emphasis on endodontics. Infection control, including biochemistry and side effects, is also presented. (Quarter 1.).

PG 520. Advanced Pharmacology II. 1 Unit.

Local anesthesia and pain management of acute and chronic pain are two main components of this lecture series, with specific emphasis on endodontics. Infection control, including biochemistry and side effects, is also presented. (Quarter 5.).