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This is an archived copy of the 2012-13 catalog. To access the most recent version of the catalog, please visit http://catalog.pacific.edu.

Chemistry

http://web.pacific.edu/x13823.xml
Phone: (209) 946-2271
Location: Classroom Building, Room 174

Andreas H. Franz and C. Michael McCallum, Co-Chairs

Programs Offered

Master of Science in Pharmaceutical and Chemical Sciences
Doctor of Philosophy in Pharmaceutical and Chemical Sciences

Specialized Areas: Bioanalytical and Physical Chemistry, Drug Design/Discovery and Chemical Synthesis, Clinical Pharmacy and Transitional Studies, Drug Targeting and Delivery, Molecular Cellular Pharmacology.

For detailed program information for these degrees please consult the Thomas J. Long School of Pharmacy and Health Sciences section in this catalog.

Chemistry Courses

CHEM 121. Organic Chemistry. 5 Units.

An Introduction to the fundamental principles of organic chemistry including molecular structure, chemical bonding, functional groups, nomenclature, stereochemistry, basic organic reactions, and modern spectroscopy for structural characterization. Three lecture periods and two three-hour laboratory periods per week are required. Prerequisites: CHEM 025, O27 with a "C-" or better.

CHEM 123. Organic Chemistry. 5 Units.

This course is a continuation of CHEM 121 with an emphasis on organic synthesis and mechanisms. The reactions of the aromatics, aldehydes, ketones, amines, carboxylic acids and their derivatives, and carbohydrates are covered. The course also touches on polymers and biological molecules including amino acids, proteins, and nucleic acids. Three lecture periods and two three-hour laboratory periods per week and are required. Prerequisite: CHEM 121 with a "C-" or better.

CHEM 132. Teaching and Learning Chemistry. 2 Units.

Students are prepared for participation in peer-led team-learning (PLTL) models of instruction in this course and it provides the opportunity for the students to become student leaders. In the PLTL, or General Chemistry Workshops, a small group of students get together under the guidance of the trained student leaders and work through a set of challenging problems prepared by the instructor of the course. The main idea is for all the students in the group to work together and gain experience and confidence solving challenging problems as a group. The Workshop provides an active teaching and learning experience. This course can be taken multiple times. Prerequisites: CHEM 025 and CHEM 027 with a "C-" or better and permission of the instructor.

CHEM 134. Teaching and Learning Organic Chemistry. 2 Units.

Student are introduced to the learning and leadership model, Peer-Led Team Learning (PLTL). The student will gain hands-on experience in leading small discussion groups in organic chemistry. Instructor-covered topics in organic chemistry include specific instructions regarding the workshop lessons, strategies in guided problem solving for the groups, and review of organic chemistry materials. Instructor-covered topics in the didactic portion of the course include, but are not limited to, practical information (understanding motivation, managing time, dealing with dominating students, learning styles, group dynamics, study skills, helping students improve critical thinking, develop logical reasoning, and prepare for tests), and a foundation in learning theory. Prerequisites: CHEM 025 and CHEM 027 with C- or better, CHEM 121 and CHEM 123 with B or better and permission of instructor.

CHEM 141. Analytical Chemistry. 4 Units.

The roots of analytical chemistry and the principles used in modern instruments come from traditional techniques. These techniques include gravimetry, acid-base, complexometric, and redox titrations form the backbone of the course, which covers most major areas of modern quantitative analysis. The theory behind the techniques is covered through many numerical examples and their applications in environmental and biochemical analyses are emphasized. Standard procedures used in analytical laboratories are introduced, including error reporting, statistics, and quality assurance. Prerequisites: CHEM 025 and CHEM 027 or GEOS 142 with a "C-" or better.

CHEM 143. Instrumental Analysis Lab. 4 Units.

Advanced analytical methodology involving electronic instrumentation is offered with emphasis on practical application and "hands-on" experience. The theory of instrumental operation is covered. Examples from modern spectroscopy, mass spectrometry, NMR, chromatography and other methods of analysis are included. Prerequisite: CHEM 141 with a "C-" or better or permission of the instructor.

CHEM 151. Biochemistry I. 4 Units.

This is the first semester of a 2 semester survey of biochemistry. The fundamental building blocks of biochemical systems are introduced covering amino acids and proteins (enzymatic & structural), nucleic acids, lipids and membranes, and carbohydrates. Particular topics of oxygen transport, exzyme kinetics, DNA replication, RNA expression, and protein expression are gone over in detail. Prerequisites: CHEM 121 and CHEM 123; CHEM 159 or CHEM 161 all with a "C-" or better; or permission of instructor.

CHEM 153. Biochemistry II. 3 Units.

As the second semester in this biochemistry series, the detailed biochemical mechanisms of the major metabolic pathways are covered. These pathways include glycolysis, gluconeogenesis, citric acid cycle, electron transport/oxidative phosphorylation, photosynthesis/Calvin cycle, lipid metabolism/fatty acid catabolism, and the synthesis/degradation of amino and nucleic acids. Discussion centers on the enzymatic mechanisms, energy, reduction/oxidation, control/regulation, and integration of these pathways. Prerequisite: CHEM 151 with a "C-" or better or permission of instructor.

CHEM 157. Biochemistry Laboratory. 4 Units.

Standard techniques used in Biochemistry. Exercises focus on the expression, mutation, and purification of a protein target and involves the following techniques: site-directed mutagenesis, column chromatography, electrophoresis, nucleic acid isolation and manipulation/use of relevant databases. Prerequisite: CHEM 151 or BIOL 169 with a "C-" or better; or permission of instructor.

CHEM 159. Biophysical Chemistry. 4 Units.

This course applies the approaches and concepts of physical chemistry to describe the reactions and phenomena in biological systems. The principles of thermodynamics, kinetics, spectroscopy and transport phenomena are covered. While this is not a mathematic intensive course, the concepts require a basic knowledge of calculus. Prerequisites: MATH 051; CHEM 025 and CHEM 027; PHYS 055 all with a "C-" or better or permission of instructor.

CHEM 161. Physical Chemistry I-Thermodynamics. 4 Units.

A classical course on equilibrium thermodynamics including the laws of thermodynamics, the Gibbs equations, the phase rule, solutions, chemical reactions, non-ideal systems, multi-component phase equilibrium and equilibrium electrochemistry. Three class periods a week are required. Prerequisites: CHEM 025, 027; MATH 055; PHYS 055 all with a "C-" or better or permission of instructor.

CHEM 163. Physical Chemistry II-Quantum Mechanics. 4 Units.

This course is a continuation of physical chemistry and includes quantum chemistry and applications, bonding, symmetry and group theory, atomic and molecular spectroscopy, and chemical kinetics. Three class periods a week are required. Prerequisites: CHEM 025 and CHEM 027; MATH 055; PHYS 055 all with a "C-" or better or permission of the instructor.

CHEM 165. Physical Chemistry III-Kinetics. 4 Units.

The fundamental principles of Chemical Kinetics are introduced in this course which covers: kinetic molecular theory of gases, rates of chemical reactions, rate laws, collision theory and chemical dynamics. Selected applications include photochemistry, catalysis, enzyme kinetics, pharmacodynamics, electrochemical systems, transport properties, viscosity, diffusion, and sedimentation. Prerequisites: CHEM 025 and CHEM 027; MATH 053 or MATH 055: PHYS 053 or PHYS 055 or permission of instructor.

CHEM 167. Experimental Physical Chemistry. 4 Units.

This laboratory course is designed to illustrate experimentally the theoretical principles and methods of thermodynamics, quantum chemistry and kinetics. It provides a research orientation through the preparation of research manuscripts and oral presentations of results. Error analysis and statistical treatment of data are emphasized. Prerequisite: CHEM 159 with a "C-" or better.

CHEM 171. Advanced Inorganic Chemistry. 4 Units.

This course includes: atomic structure, periodicity, covalent bonding theory, molecular geometry and symmetry, molecular orbital theory and its applications. Also covers coordination and organometallic chemistry, ligand field theory, spectroscopy, structure, reaction mechanisms, introduction to bioinorganic chemistry and metals in medicine. Two class periods and four hours of laboratory per week are required. Prerequisite: CHEM 163 with a "C-" or better or permission of the instructor.

CHEM 181. Intro to Molecular Simulation. 4 Units.

This course enables chemistry and other science students to utilize computational tools for molecular simulation. Students who complete this class are able to understand the theory behind molecular dynamics and force-fields. In addition, students construct and execute molecular simulations using standard tools such as CHARMM, NAMD, VMD and GAUSSIAN. Students then demonstrate an ability to analyze and present the data obtained from such simulations. Prerequisites: CHEM 025 and CHEM 027 with a grade of C- or better and instructor approval.

CHEM 191. Independent Study. 2-4 Units.

CHEM 193. Special Topics. 4 Units.

CHEM 197. Independent Research. 1-4 Unit.

Prerequisite: CHEM 025 with a "C-" or better.

CHEM 197D. Independent Research. 1-4 Unit.

CHEM 197E. Independent Research. 1-4 Unit.

CHEM 197F. Independent Research. 1-4 Unit.

CHEM 197G. Independent Research. 1-4 Unit.

CHEM 234. Selected Topics: Organic Chemistry. 4 Units.

Topics presented at various times under this course description include physical organic, natural products and structure elucidation, stereochemistry, heterocycles and carbohydrate chemistry.

CHEM 243. Advanced Instrumental Analysis Lab. 4 Units.

Comprehensive investigation of absorption, emission, partition and electrical methods of chemical analysis. Theoretical basis and practical experience are combined in a total course. Some background in elementary optics and electronics useful but not required.

CHEM 245. Advanced Instrumental Methods. 4 Units.

Team-taught course. Students select from a number of instrumental projects, including: FTNMR, GC-mass spectrometry, advanced electrochemical techniques, high pressure liquid chromatography, photochemistry, fluorescence and phosphorescence and radioimmunoassay.

CHEM 264. Selected Topics - Physical Chemistry. 4 Units.

Topics presented at various times under this course description include: advanced thermodynamics, statistical mechanics, physical chemistry of solutions, physical methods in chemistry, photoluminescence and molecular photochemistry, and advanced kinetics. Permission of the instructor required.

CHEM 271. Advanced Inorganic/Bioinorganic Chemistry. 4 Units.

Review of basic concepts; descriptive transition metal chemistry; studies in main group and coordination chemistry; inorganic chemistry in biological systems; organometallic systems. Permission of the instructor required.

CHEM 274. Selected Topics - Inorganic Chemistry. 4 Units.

Topics presented at various times under this course description include: mechanisms of inorganic reactions, bonding theory, physical methods, nuclear chemistry and geochemistry.

CHEM 291. Independent Study. 2-4 Units.

CHEM 293. Special Topics. 3 OR 4 Units.

CHEM 295. Graduate Seminar. 2 Units.

CHEM 297. Graduate Research. 1-4 Unit.

CHEM 299. Thesis. 1-4 Unit.

CHEM 381. Apprentice Teaching. 1-4 Unit.

CHEM 391. Independent Study. 2-4 Units.

CHEM 395. Tchg. Sem. in the Clg. Chem.. 2 Units.

CHEM 397. Graduate Research. 1-6 Unit.

CHEM 399. Dissertation. 1-6 Unit.

Pharm & Chem Sciences Courses

PCSP 201. Statistics and Experimental Design. 3 Units.

This course involves the study of the application and limitations of statistical methods of inference as they apply to the fields of chemistry and the pharmaceutical sciences. Topics include the use of parametric statistics for statistical inference, comparisons of means, analysis of variance and linear regression. Parametric statistics and nonparametric measures of association and elements of good experimental design are also included. Graduate standing.

PCSP 203. Information and Laboratory Management. 1 Unit.

This course covers basic knowledge of Information Management, Intellectual Property and Patenting, Research Laboratory Operations and Safety, Good Maintenance Practice (GMP) and Good Clinical Practice (GCP). Graduate standing.

PCSP 204. Introduction to Nanotechnology. 4 Units.

The course provides an overview of Molecular Nanotechnology. It shows that the nano regime is so different from other regimes because both classical and quantum effects can be active, thus leading to unique properties of nano devices. MNT is a highly interdisciplinary science, which will be reflected in the course by making reference to physics, chemistry, biology, pharmacy and engineering. Applications of MNT, as they are already in use today or as they are planned for the future, will be discussed. Graduate standing or permission of instructor.

PCSP 205. Instrumental Analytical Chemistry. 4 Units.

Lectures focus on the theory and physical principles of instruments for the analysis of matter. Laboratory lecturer describes the actual operation of instruments. Students gain hands-on experience with the operation of instruments. Graduate standing.

PCSP 206. Models and Concepts in Chemistry. 4 Units.

The course focuses on a general understanding of chemistry in terms of models and concepts that describe structure, stability, reactivity and other properties of molecules in a simple, yet very effective way. Many chemical problems from organic, inorganic, and transition metal chemistry and biochemistry are presented and the applicability of the various models and concepts as well as their limitations are demonstrated. Graduate standing or permission of instructor.

PCSP 207. Bioanalytical Techniques. 3 Units.

Students are introduced to techniques of bioanalysis for the pharmaceutical and chemical sciences. The course provides a conceptual understanding and practical familiarity with techniques used for analysis of proteins and nucleic acids. Recommended: Basic biochemistry.

PCSP 208. Applied Pharmaceutical Analysis. 4 Units.

Students study analytical methods applied for the assessment of pharmaceutical quality, and the identification and quantification of active pharmaceutical molecules and metabolities in biological samples. Prerequisite: any analytical Chemistry or Biology background and permission of instructor.

PCSP 209. Technical Writing and Presentation. 1 Unit.

This course covers common written and oral forms of communication and scientific material. Graduate standing.

PCSP 211. Drug Design. 4 Units.

Students study modern methods used in the design of new drugs. Target selection, lead compound discovery and molecular modifications to optimize activity are studied. Graduate standing or bachelor's degree and permission of instructor.

PCSP 213. Biotransformation of Pharmaceutical Agents. 3 Units.

This course teaches the graduate students the chemical and biological principles of the transformations of pharmaceutical agents in the body and the impact of such transformations on pharmacokinetics, pharmacodynamics, toxicity, drug design and drug delivery. Graduate standing in TJ Long School of Pharmacy & Health Sciences or in Chemistry Department, or permission of instructor.

PCSP 215. Molecular Modeling and Drug Design. 4 Units.

The course presents a thorough and in-depth overview of methods and techniques in computer assisted drug design (CADD) where especially the needs of the pharmaceutical industry are considered. Graduate standing or permission of instructor.

PCSP 217. Drug Biotransformation. 3 Units.

This course generally meets two times a week (two 75 minute lectures per week). In this course, a mechanistic approach is employed to study human drug metabolizing enzymes. Other aspects related to the differential expression of these enzymes are discussed. Students need to submit a research proposal at the end of the course. Graduate standing or permission of instructor.

PCSP 221. Fundamentals of Dosage Forms. 3 Units.

In this course the fundamental physicochemical properties and composition of various dosage forms is taught. Graduate standing.

PCSP 222. Thermodynamics of Pharmaceutical Systems. 3 Units.

This is a classical course on the applications of thermodynamics to the study of pharmaceutical systems. The course includes a review of the basic principles of thermodynamics. These principles are used to describe and study physical and chemical transformations of pure substances and mixtures in pharmaceutical systems. Graduate standing or permission of instructor.

PCSP 223. Phamacokinetics and Pharmacodynamics. 3 Units.

This course teaches critical concepts and basic principles of pharmacokinetics and pharmacodynamics. Such concepts and principles are required for the students to understand the drug behavior in the body. Graduate standing or permission of instructor.

PCSP 224. Diffusion in Pharmaceutical Sciences. 3 Units.

Students discuss diffusion theories, experimental methods, and application to pharmaceutical/biological systems. Prerequisites: CHEM 161 and MATH 033 or equivalent or permission of instructor.

PCSP 225. Pharmaceutical Technologies. 2 Units.

Students study theory and practice in industrial pharmacy that include pre-formulation, formulation and pharmaceutical manufacture. Prerequisites: PHAR 114, 123, 133. Graduate standing.

PCSP 228. Mathematical Modeling in Pharmaceutical Research. 3 Units.

Students study the mathematical modeling theory and application to problems in pharmaceutical research. Modeling is applied to three major areas: drug delivery, metabolic/biological cascades and pharmacological response kinetics. Prerequisites: PHAR 113 or permission of instructor. Recommended: MATH 057; PHAR 114 and PHAR 134.

PCSP 229. Advances in Drug Delivery Systems. 3 Units.

In this course the design and formulation/fabrication of controlled release and other novel drug delivery systems for oral, transdermal, ocular and other routes of delivery are covered. The biopharmaceutical rational and evaluation of such systems is also discussed. Graduate standing.

PCSP 230. Molecular Pharmacology of Nucleic Acid. 3 Units.

Students study the mechanisms by which drugs and other chemicals can affect gene expression and cell division through actions on DNA structure and nucleic acid and protein metabolism. Graduate standing.

PCSP 231. Molecular Pharmacology I. 4 Units.

This is the first course in the Molecular Pharmacology series, effects of autonomic and central nervous system therapeutic agents and the mechanisms whereby these effects are induced. Drug classes are presented to illustrate the effects of drug classes in the treatment of disease. The molecular principles of drug action and receptor theory are covered. Enrollment in the PCSP program is required.

PCSP 232. Mechanisms of Drug Addiction II. 4 Units.

This is the second course in the Molecular Pharmacology series, effects of cardiovascular, endocrine, cancer chemotherapy, immunologic therapeutic agents and the mechanisms whereby these effects are induced. Drug classes will be presented to illustrate the effects of drug classes in the treatment of diseases. Enrollment in the PCSP program is required.

PCSP 233. Molecular Pharmacology III. 4 Units.

This is the third course in the Molecular pharmacology series, effects of antimicrobial, hematologic and gastrointestinal therapeutic agents and the mechanism whereby these are induced. Drug classes are presented to illustrate the effects of drug classes in the treatment of diseases. The mechanisms of drug toxicity are also covered. Enrollment in the PCSP program is required.

PCSP 234. Neurochemical Pharmacology. 3 Units.

Students study neurobiology of nerve cells and the neurochemical pharmacology associated with function of central and peripheral nervous systems. Graduate standing.

PCSP 235. Current Topics in Pharmacology and Toxicology. 2 Units.

Each week this course focuses on a different area of research interest in pharmacology and toxicology. It involves discussions of assigned research papers that provide students with a current perspective and understanding of issues and techniques associated with the selected research topics. Graduate standing in the PCSP program.

PCSP 236. Selected Topics: Advanced Toxicology. 2 Units.

This course teaches students the organ systems and mechanistic approach to toxicological assessment. Quantitative, environmental and regulatory aspects of toxicology are included as essential elements of toxicological evaluation. Graduate standing in the PCSP program or permission of instructor.

PCSP 237. Cell Culture Techniques. 3 Units.

This course teaches students basic techniques in mammalian cell culture. In addition, advanced topics of cellular techniques are demonstrated and discussed representative of current research methods. Permission of PCSP Program Director.

PCSP 240. Molecular Spectroscopy. 4 Units.

The basic theory behind infrared, visible, ultraviolet, and magnetic resonance spectroscopy are studied. The course includes the quantum mechanics of light absorption, atomic absorption and emission spectroscopy, vibrational spectroscopy of diatomic and polyatomic molecules, absorption and emission electronic spectroscopy and magnetic resonance spectroscopy. Graduate standing or permission of instructor.

PCSP 241. Advanced Organic/Bioorganic Chemistry. 4 Units.

Synthetically useful organic reactions not normally covered in the introductory courses are emphasized. The reactions are grouped according to their mechanistic type and discussed in terms of their reaction mechanisms and synthetic utility. Prerequisites: CHEM 121 and CHEM 123 with a "C" or better.

PCSP 242. Selected Topics: Advanced Organic Chemistry. 4 Units.

Topics presented at various times under this course description include: Physical organic, natural products and structure elucidation, stereochemistry, heterocycles and carbohydrate chemistry. Prerequisites: CHEM 121 and CHEM 123 with a "C" or better.

PCSP 243. Applied Computational Chemistry. 4 Units.

Besides the normal laboratory experiments traditionally expected, modern chemists/biochemists, whether in the chemical/pharmaceutical industry or academia, perform "experiments" on the computer by calculating the outcome of chemical and biochemical reactions. This in silico chemistry has become an integral part of the education in chemistry and the present course will provide an introduction into this field by addressing a general audience of chemists/biochemists and students from neighboring fields.

PCSP 244. High-Resolution NMR Spectroscopy. 4 Units.

A study of one and two dimensional FT-NMR techniques used for structure elucidation of organic molecules. Emphasis is placed on understanding the capabilities and limitations of these techniques, the information they provide and the practical aspects of their implementation. Permission of instructor.

PCSP 245. Proteins and Nucleic Acids. 3 Units.

Students study the chemical, physical and biological properties of the proteins and nucleic acids and their constituents. Topics include isolation, determination of composition, sequence and structure; correlation of structure and biological properties. Prerequisite: CHEM 151 with a "C" or better.

PCSP 247. Mass Spectrometry. 4 Units.

Students study the fundamentals of mass spectrometry, theory, instrumentation and applications to organic and biological molecules. Prerequisite: PCSP 205.

PCSP 248. Enzymology. 4 Units.

This class gives an introduction into the biochemistry of the various classes of enzymes with emphasis on laboratory techniques. Prerequisite: CHEM 151 with a "C" or better.

PCSP 254. Research Processes: Publications, Presentations, Grants and IRB. 3 Units.

This course prepares graduate students in Pharmacoeconomics and Health Care Outcomes and Services as a successful researcher by gaining experience in the development of a research plan, obtaining approval of the Institutional Review Board, submission of an extramural grant, dissemination of the student findings at a national or international meeting, and submission of a manuscript to a peer-reviewed journal. Prerequisite may be taken concurrently: PCSP 201, or other comparable statistics course at the discretion of the course coordinator. Permission of the instructor is required.

PCSP 255. Long Term Care Practice. 3 Units.

This class covers the clinical pharmacy component of a long term facility with special emphasis on opportunities and research needs. Students study the systematic approach to monitor the drug therapy of the long term care patient. Graduate standing.

PCSP 256. Health Services Management and Finance. 2 Units.

Health Care Finance offers an introduction to accounting, financial theory and practice in health care settings. It is designed to familiarized students with financial concepts and issues confronting managers in the health and pharmaceutical sectors. Prerequisites: Admission to the PCSP graduate program and permission of the instructor.

PCSP 257. Ambulatory Care Practice. 3 Units.

Students examine the application of clinical pharmacy to ambulatory care settings in an affiliated clinic or community pharmacy. Special emphasis is placed on opportunities and research needs. Graduate standing.

PCSP 258. Teaching and Evaluation of Learning and Competency. 2 Units.

Student abilities in development as a teacher are developed in an interactive, evidence-based manner covering the major components of teaching, learning, evaluation and assessment. Prerequisites: Admission to the PCSP graduate program and permission of the instructor.

PCSP 259. Topics in Acute Case Practice. 3 Units.

Students examine the application and investigation of clinical pharmacy in acute care setting with emphasis on medical management of common diseases and rational drug selection and dosing. Graduate standing.

PCSP 260. Advances in Neuropsychiatric Pharmaceutical Care. 2 Units.

Students examine pharmaceutical care for the patient with neurologic and psychiatric disorders. Emphasis is placed on appropriate use of drug therapy in the management of these disorders. Graduate standing. Permission of instructor.

PCSP 261. Advances in Cardiovascular Pharmaceutical Care. 3 Units.

Students explore the application of Drug Therapy to patient care with assignments that expand the students' knowledge of background material that support therapeutic guidelines. Permission of instructor.

PCSP 262. Vascular, Renal and Pulmonary Care. 4 Units.

Students study the pharmaceutical care for the patient with cardiovascular, respiratory and renal diseases. Emphasis is placed on appropriate use of drug therapy in the management of the disease. Prerequisites: Successful completion of all courses in semesters 1-3 of the Doctor of Pharmacy Program.

PCSP 263. Analytical Techniques in Pharmaceconomics and Health Care Outcomes and Services. 4 Units.

This course prepares graduate students in Pharmacoeconomics and Health Care Outcomes and Services to meet the challenges of a broad assortment of health services related research by providing fundamental principles and tools for the discipline. The class uses real world examples of research design, statistical evaluations and database selection and use to assess therapeutic, economic and humanistic outcomes. Prerequisites: PCSP 201 and PCSP 203.

PCSP 264. Health Serv Rsrch Analysis. 3 Units.

This course prepares graduate students in Pharmacoeconomics and Health Care Outcomes and Services to meet the challenges posed by the needed to rapidly and accurately review, critique and assimilate information from health care and economic literature and to complete a full, advanced statistical analysis such as that required for the introduction and discussion sections of a research article or dissertation in pharmacoeconomics and health care outcomes. Prerequisites: PCSP 201, 203, 263.

PCSP 265. Health Care Economics. 2 Units.

This course is a current medical literature based course and is designed to prepare graduate students in Pharmacoeconomics and Health Care Outcomes and Services to meet challenges associated with understanding microeconomics terms and tools used in health care, medical literature and health care decision making processes. Readings, lectures and discussions emphasize processes used in economic decisions made by health care consumers, providers and third party payers. Primary topics include the demand for health care, how it may vary based on payment/payer options and the scope and supply of care available. Prerequisites: PCSP 263, 264, and permission of the instructor.

PCSP 266. Pharmacoeconomics and Microeconomics/Managerial Economics. 2 Units.

This course is designed to prepare graduate students in Pharmacoeconomics and Health Care Outcomes and Services to evaluate the applicability, importance and relevancy of pharmacoeconomics, microeconomics and managerial economics in answering questions and solving problems within the US health care system. Additionally, after completion of this course, students can assess, apply, interpret and determine the appropriate utilization of pharmacoeconomics, microeconomic, and managerial economic principles to address relevant healthcare issues and questions. Prerequisites: PCSP 201 and permission of the instructor.

PCSP 270. Theory and Methodology of Simulation of Natural Rock Formation. 4 Units.

This course is created particularly for PhD students of the Pharmaceutical and Chemical Sciences Program. It offers a comprehensive integration of multi-disciplinary sciences such as biology, life science, geoscience, ocean science, environment science, material science, etc. The course introduces some new breakthroughs and frontier discovery which reveal the mystery relationship between life science and geoscience. Upon completion of this course, PhD students are able to carry out professional lab and on-site tests and measurements. Graduate standing in chemistry, biology, geology, material science, environmental science or engineering or permission of instructor.

PCSP 283. Multidisciplinary Project. 1 Unit.

Students in the Pharmaceutical and Chemical Science Graduate Program design an interdisciplinary project based upon the relevant contributions of their backgrounds. Enrollment in PCS Graduate Program.

PCSP 287. Internship. 1-4 Unit.

The internship offers an experiential learning program at a pharmaceutical/chemical/biotechnological industry, academic institution, government laboratory, or a clinical site that entitles the students to learn advanced techniques and practical application of the theoretical principles learned in a number of courses. Graduate students that have completed Category I course work, or obtained permission of coordinator shall enroll in this course. For students in thesis/dissertation tracks, concurrence of thesis/dissertation adviser(s) is required.

PCSP 291. Independent Study. 1-4 Unit.

Independent Study is restricted to masters or doctoral (PhD) candidates. It may be repeated with permission as progress warrants. No more than eight credits may be used toward doctoral degree requirements. The student must be in good academic standing. Approval of the required contract for Independent Graduate Study is required. Graduate standing and permission of the instructor.

PCSP 295. Graduate Seminar. 1 Unit.

This seminar presents research-related topics given by both PCSP faculty and graduate students. Enrolled students are required to attend all seminars given throughout the pharmacy academic year and to give one seminar in that year. This course is required for all graduate students for the first three years of their tenure in the PCSP. Students who have already enrolled in this course for three years are encouraged to attend seminars without official enrollment. PCSP faculty members present a short talk on their research areas at the beginning of the fall semester each year. Graduate standing.

PCSP 297. Graduate Research. 1-4 Unit.

Graduate Research is limited to masters or doctoral (PhD) candidates. It may be repeated with permission as progress warrants. No more than eight credits may be used toward doctoral degree requirements. Admission to the graduate program and permission of research director.

PCSP 299. Thesis. 1-6 Unit.

This course provides one-to-one work by student with faculty research mentor to plan, organize, conduct, evaluate and write an original research project as a thesis for partial fulfillment of the MS degree. Admission to MS thesis program (PCSP) and permission of research advisor.

PCSP 387. Internship. 1-4 Unit.

This internship offers an experiential learning program at a pharmaceutical/chemical/biotechnological industry, academic institution, government laboratory, or a clinical site that entitles the students to learn advanced techniques and practical application of the theoretical principles learned in a number of courses. Graduate Standing with completed Category I course work or permission of coordinator. For students in thesis/dissertation tracks, concurrence of thesis/dissertation adviser(s) is required.

PCSP 391. Independent Study. 1-4 Unit.

Indpependent Study is restricted to masters or doctoral (PhD) candidates. It may be repeated with permission as progress warrants. No more than eight credits may be used toward doctoral degree requirements. The student must be in good academic standing. Approval of the required contract for Independent Graduate Study is required. Graduate standing and permission of the instructor.

PCSP 391D. Independent Study. 1-4 Unit.

PCSP 395. Graduate Seminar. 1 Unit.

This seminar presents research-related topics given by both PCSP faculty and graduate students. Enrolled students are required to attend all seminars given throughout the pharmacy academic year and to give one seminar in that year. This course is required for all graduate students for the first three years of their tenure in the PCSP. Students who have already enrolled in this course for three years are encouraged to attend seminars without official enrollment. PCSP faculty members present a short talk on their research areas at the beginning of the fall semester each year. Graduate standing.

PCSP 397. Graduate Research. 1-4 Unit.

Graduate Research is limited to masters or doctoral (PhD) candidates. It may be repeated with permission as progress warrants. No more than eight credits may be used toward doctoral degree requirements. Admission to the graduate program and permission of research director.

PCSP 397D. Graduate Research. 1-4 Unit.

PCSP 397E. Graduate Research. 1-4 Unit.

PCSP 399. Dissertation. 1-6 Unit.

This course is only open to doctoral (PhD) candidates. No more than eight credits may be used toward doctoral degree requirements. Admission to PhD program (PCSP) and permission of research advisor.

Chemistry Faculty

Andreas Franz, Associate Professor and Co-Chair, 2002, BS, Universitaet-Gesamthochschule Siegen, 1994; MS, University of the Pacific, 1997; PhD, University of the Pacific, 2000.

C. Michael McCallum, Professor and Co-Chair, 1994, BS, Michigan State University, 1988; PhD, University of California, Berkeley, 1993.

Ryan Moffet, Assistant Professor, 2011, BS, San Francisco State University, 2002; PhD, University of California San Diego, 2007

Jianhua Ren, Associate Professor, 2002, BS, Beijing Normal University, 1986; MS, Auburn University, 1994; PhD, Purdue University, 1999.

Silvio Rodriguez, Professor, 1978, BS, University of Chile, 1968; MS, University of California Santa Barbara, 1970; PhD, University of California Santa Barbara, 1978.

Vyacheslav V. Samoshin, Professor, 1999, MS, Lomonosov Moscow State University, USSR, 1974; PhD, Moscow State University 1982; DSci, Moscow State University, 1991.

Bálint Sztáray, Associate Professor, 2008, MS, Eötvös Loránd University, 1997; PhD, Eötvös Loránd University, 2001.

Jerry Tsai, 2008, BS, University of California, Los Angeles, 1991; PhD, Stanford University, 1998.

Liang Xue, Assistant Professor, 2007, BS, Fudan University, Shanghai, China, 1996; PhD, Clemson University, 2004.

Qinliang Zhao, Assistant Professor, 2010, BS, Zhejiang University, 2003; PhD, Texas A & M University, 2007